Understanding Pulmonary Embolism
Pulmonary Embolism (PE) is a serious condition that occurs when a blood clot blocks one of the arteries supplying the lungs. In many cases, the clot develops in the deep veins of the legs or pelvis—a condition known as Deep Vein Thrombosis (DVT)—and travels through the bloodstream to the lungs.
A pulmonary embolism can range from a small clot causing mild symptoms to a large blockage that can significantly affect the heart and lungs. Early diagnosis and timely treatment are essential to prevent serious complications.
Symptoms of Pulmonary Embolism
Symptoms can appear suddenly and may include:
- Sudden shortness of breath
- Chest pain, particularly pain that worsens with deep breathing
- Rapid or irregular heartbeat
- Unexplained cough, sometimes with blood
- Dizziness or fainting
- Unusual anxiety or restlessness
- Leg pain, swelling, warmth or tenderness, particularly with DVT
The severity of symptoms depends on the size and location of the clot and the overall health of the patient.
Causes and Risk Factors
Pulmonary embolism most commonly results from a blood clot originating in the deep veins of the legs. Risk factors may include:
- Prolonged immobility or long-distance travel
- Recent surgery or hospitalization
- Previous DVT or pulmonary embolism
- Certain heart or blood disorders
- Cancer and some cancer treatments
- Pregnancy and the postpartum period
- Obesity
- Smoking
- Use of certain hormone-based medications

Diagnosis
Doctors may use a combination of clinical assessment and diagnostic tests to identify pulmonary embolism. These may include:
- CT Pulmonary Angiography (CTPA)
- Blood tests such as D-dimer
- ECG and echocardiography
- Doppler ultrasound of the legs
- Other imaging or blood tests when required
Treatment
Treatment depends on the size of the clot, symptoms, risk level and the patient’s overall condition. It may include:
- Anticoagulant medicines (blood thinners) to prevent clot growth and new clots
- Thrombolytic therapy in selected patients with severe or life-threatening PE
- Catheter-directed procedures to remove or dissolve the clot in appropriate cases
- Surgical or mechanical clot removal in selected high-risk situations
- Treatment of the underlying cause and prevention of recurrent clots
When to Seek Emergency Medical Care
Sudden breathlessness, severe chest pain, coughing up blood, rapid heartbeat, dizziness or fainting can be signs of a potentially life-threatening pulmonary embolism. Immediate medical evaluation is important.
Expert Care for Pulmonary Embolism
Pulmonary embolism requires prompt assessment and an individualized treatment approach. With appropriate diagnosis, risk assessment and timely intervention, many patients can be treated effectively and the risk of recurrence can be reduced.
Dr. Shashi Vardhan Janjirala provides specialized cardiovascular and endovascular care, including evaluation and management of vascular conditions associated with blood clots and pulmonary embolism.